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At the same time, GLP-1 receptor activation reduces the activity of pathogenic Th1 and Th17 cells, the effector T cells most directly responsible for autoimmune tissue damage

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For example, semaglutide 2.4mg (Wegovy) has demonstrated approximately 15% weight loss at 68 weeks in clinical trials, while liraglutide 3mg (Saxenda) typically achieves around 8% at 56 weeks

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