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2007;65(Suppl 1):S4-10
The anticancer drug DOX and SOR are finally loaded onto SPMM via hydrogen bonds, ionic bonds, and/or coordination bonds to construct D/S@SPMM
Their short half-lives mean timing matters: administration is conventionally described around bedtime or after fasting, aiming to align the induced pulse with the body's own nocturnal GH release and to avoid the GH-blunting effect of elevated insulin after meals
Clinical studies have shown that consistent use may lead to visible improvements in skin pigmentation in as little as four weeks
There were 2 large human trials with 117 and 320 patients each, but neither showed any benefits after 7-10 days of administration
Leaves skin soft, smooth, and refreshed
