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Microplastics induce intestinal inflammation, oxidative stress, and disorders of metabolome and microbiome in zebrafish

Increased lipid peroxidation activates iron-dependent pathways that generate toxic lipid radicals, prompting cell demise

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They reported a decreased melanin index measured at six body sites (but statistically significant only at two sites, namely the right side of the face ( p =0.021) and the sun-exposed left forearm ( p =0.036))

No finished-drug approval, no active IND, and no FDA-registered human clinical trials as of April 2026

BPC 157 Rescued NSAID-Cytotoxicity via Stabilizing Intestinal Permeability and Enhancing Cytoprotection