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Because retatrutide is not yet licensed in the UK, it is not routinely available for prescribing outside a clinical trial or a specific MHRA access scheme (such as the Early Access to Medicines Scheme [EAMS] or named-patient unlicensed supply)

Nasal bleeding[6]

So while Ozempic is a peptide, its also a lightning rod for controversy, thanks to its meteoric rise in popularity and the ethical questions around access and use

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Emerging dual agonists, such as survodutide and cotadutide, which target GLP-1 and glucagon receptors, are being explored for treating metabolically associated fatty liver disease and may also address fatty kidney, a key factor in CKD related to visceral obesity [48]