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The GSH/GSSG ratio maintains ~100:1 at steady state but decreases to 10:1 or less under oxidative stress

May be a marker of underlying disease (e.g., liver disease, malignancy, MDS/CML)

Nat Immunol (2017) 18: 71624

Milligram-level solids at these amounts sit near or below the resolution of typical consumer scales, which is one more reason the communitys precision claims should be read skeptically

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Supplement Facts Active ingredient : Lipoic acid Alternate name(s) : Lipoid acid, thioctic acid Recommended dose : Generally, 600 to 1,200 milligrams (mg) daily Safety considerations : Overall, it's safe, though it may interfere with some medications and can cause mild gastrointestinal side effects.