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Durante el periodo periconcepcional y preimplantacional factores como el estado nutricional y estrs de la madre, o niveles de hormonas y oxgeno, afectan el desarrollo del oocito y el blastocisto alterando el nmero de clulas destinadas a trofoblasto y el potencial de crecimiento de la placenta44,45
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[1] The inflammation seen in KP could be caused by repeated mechanical irritation of the hyperkeratotic plugs, including scratching, but also by a decrease in antimicrobial peptides with accreted bacteria colonization, due to loss of sebaceous gland-derived antimicrobial peptides
doi: 10.1002/mnfr.201200131 245
Finally, real-world validation through clinical trials is essential to confirm the models practical effectiveness in medical settings
If any of these symptoms appear, discontinue use immediately and consult a dermatologist
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