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Before GLP treatment (blue curve), minimum HR initially increases slightly when exercise exceeds the rolling baseline but then declines substantially at very large deviations

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Endoscopic procedures, particularly endoscopic sleeve gastroplasty, offer a favorable safety profile and are an alternative for patients who do not want to undergo metabolic-bariatric surgery, though they currently lack insurance coverage in the United States

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Always consult a qualified healthcare professional before making changes to your diet or supplement routine