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In vivo , FTO knockdown significantly elevates YTHDF2 expression in the striatum of PD mice, inhibits m 6 A demethylation of BAP1 and reduces BAP1 expression, upregulates SLC7A11 expression, decreases -Syn, MDA, Fe 2+ , and 4-HNE levels, suppresses neuronal ferroptosis and disruptions in the amino acid antioxidant system, and promotes dopaminergic neuronal survival in PD mice (Li et al., 2025c)

How are GLP-1 RAs Changing T2D Treatment Options Many patients have reported positive experiences with GLP-1 receptor agonists

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K., Zhang, S., Selvin, E

This led to two distinct pharmaceutical strategies

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