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MT-1s MC1R-preferential activity makes it the primary research tool for studying MC1R biology in pigmentation, photoprotection, and skin immunology without the confounding central melanocortin receptor activation that limits the interpretability of studies using less selective melanocortin agonists

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Melanotan II, also known as MT-2, is a synthetic melanocortin peptide studied in laboratory research involving peptide chemistry, receptor biology, molecular signaling, cellular communication, and experimental peptide models

The improvement of this functional marker may indicate an important pathway towards new therapeutic strategies that target glutathione dysregulation in schizophrenia

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