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[112] found a decrease in LFC in patients with moderate to severe NAFLD with T2DM using exenatide in combination with dapagliflozin

It reduces inflammation, stimulates cell growth, and increases blood flow to the injured area, creating an optimal environment for tissue repair

In cell and animal studies, it acts as a selective inhibitor of nicotinamide Nmethyltransferase (NNMT)

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Brakedal B, et al

companies are examining compounds that mimic bacterial metabolites but are more drug-like (improved stability, BBB penetration)