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5-Amino-1MQ is frequently used in laboratory investigations involving cellular and molecular research models
J Laryngol Otol 93:11911199
PubMed PMID: 31959736
It immediately supplies cysteine for repletion of glutathione and thus, recovery from toxicity
Under basal homeostatic conditions, Nrf2 is sequestered in the cytoplasm through its interaction with the adaptor protein KEAP1 (Kelch-like ECH-associated protein 1), which targets Nrf2 for ubiquitination and subsequent proteasomal degradation
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