In the Phase 2 trial, the defined 1 mg weekly dose produced 8.7% mean weight loss over 48 weeks versus 2.1% with placebo clinically meaningful, but roughly a third of the 12 mg result (24.2%)
Meta-analyses report a pattern of ALC deficiency in DPN patients 2 and a growing number of randomized controlled trials on ALC suggests that ALC is not only safe and effective, but also outperforms placebo in reducing diabetes-related neuropathic pain 3,4
doi:10.1002/14651858.CD007411.pub4
FOOTNOTES *KLOwen Orthodontics, Richardson, TX
However, individuals with Prader-Willi syndrome can potentially live until their 70s if they maintain a healthy weight
Since it enhances growth hormone production, its prohibited in professional and competitive sports