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TRIUMPH-1 (NCT05929066) will look at the efficacy and safety of retatrutide in people with overweight/obesity without T2D and will include subsets of participants with knee osteoarthritis (OA) or OSA

Because of that effect, some prescribers may use semaglutide off-label in selected adults who need support with weight management, insulin resistance, or metabolic risk reduction

This is fundamentally different from how minoxidil works, which primarily dilates blood vessels, or how finasteride works, which blocks DHT production

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