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Key Takeaways GLP-1 medications can slow digestion, which may contribute to constipation, bloating, cramping, and other GI symptoms

The GIP component enhances insulin secretion in response to meals while also appearing to buffer some of the nausea commonly associated with GLP-1 activation

Along with the improvements in inflammation that occur due to weight loss and improved insulin sensitivity, GLPs appear to directly modulate the immune system by engaging receptors on immune cells