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Finally, following recent concerns by regulatory agencies regarding a potential increase in suicidal behavior associated with GLP-1RAs 206 , we found 1 recent pharmacovigilance report showing 0.6% suicidal events among 41,236 safety reports for these medications 207 and an emulated target trial of 86,418 older adults with T2DM that did not identify any difference in suicidal ideation or behavior between GLP-1RAs and other antidiabetic medications over 1.5 years 208

FOCUS ON NUTRITIONAL BALANCE Creating a calorie deficit is important for weight loss, but it is just as important to make sure your meals include the right balance of macronutrients

doi: 10.3390/ijms19082287 56 Otulak-KozieK.KozieE.HorvthE.CsiszrJ

Thanks for sharing Lauren!

These medicines are usually given as injections or pills and work best when combined with healthy eating and regular physical activity