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A comprehensive review published in Frontiers in Endocrinology (2024) further confirms that GLP-1 drugs reshape gastrointestinal physiology and metabolic regulation at multiple levels, affecting far more than just appetite

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The authors reported that the metabolite Ac-LKKTE showed greater wound-closure activity in their fibroblast assay than the parent fragment

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Low WY, Feil SC, Ng HL, Gorman MA, Morton CJ, Pyke J

4-Hydroxyalk-2-enals are substrates for glutathione transferase