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The backbone derives from features of glucagon the ancestral peptide that gave rise to GLP-1 and GIP evolutionarily with modifications that create the specific receptor-activity ratio Eli Lilly targeted

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Andrologia 54 , e14617

However, WMSPI had the highest fat content, which could be due to the poor fat removal in the meal as evident in the high fat content of the water-extracted meal (Table 1)