when does the patent for tirzepatide expire expiry expiration eli lilly Tirzepatide's primary patents in 2036 but Eli Lilly has Is There a Generic Tirzepatide?

Importantly, the 2024 systematic review by Sikiric et al

A 2020 meta-analysis published in The BMJ (k=129 studies, N=10,069,955) found that prediabetes was associated with a 15% increased risk of all-cause mortality, a 13% increased risk of cardiovascular disease, and a 16% increased risk of stroke compared with normoglycemia [13]

10.1016/j.mce.2015.02.017 17 SodhiM.RezaeianzadehR.KezouhA.EtminanM

A prospective cohort study involving 266 elderly adults treated with epithalamin (the parent compound from which Epithalon was derived) over 2-3 years with subsequent 4-5 year follow-up demonstrated mortality reduction of 28% overall, with a 2-fold decrease in cardiovascular disease-specific mortality

Episode is in the comments

Compounded GLP-1s come with their own risks