2, the meta-analysis of all available cohorts showed a significant reduction in risk for schizophrenia (OR = 0.72, 95% CI [0.610.86]), bipolar disorder (OR = 0.91, 95% CI [0.880.94]), bulimia nervosa (OR = 0.34, 95% CI [0.230.52]), PTSD (OR = 0.45, 95% CI [0.310.67]), and autism (OR = 0.55, 95% CI [0.320.93])
However, Lillys particular rapid growth signals that while first-mover advantage in a high-demand disease area matters, it doesnt guarantee staying on top
Atack J., Lavreysen H
You lose the synergistic pulse effect that makes the combination valuable
But the principle here is sleep
I observe that trials progress through three phases, each with more participants, to assess effectiveness, side effects, and safe dosages