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His team is best known for identifying MOTS -c, which has been called an exercise mimetic: it activates cellular pathways that are usually turned on during exercise

Gut health restoration happens through stomach lining protection, ulcer healing, and tight junction repair

The Trx-based system also regulates redox-sensitive transcription factors such as p53, which, when activated by oxidative stress, supports cell survival mechanisms in conditions with high ROS

This mechanism has been characterised in multiple pre-clinical studies, with particular focus on tendon and ligament repair outcomes

Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

In humans, members of the following classes of cytosolic GSTs are present: alpha, zeta, theta, mu, pi, sigma and omega 6