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Hepatic histopathology (Fig.4-A, B) showed that both semaglutide and tirzepatide significantly reduced the non-alcoholic fatty liver disease activity score (NAS) by decreasing steatosis and cell ballooning, compared to the non-restricted diet model group

Concurrently, fibrosis improvement occurred in 59.1%, 53.3%, and 54.2% of patients across the three dose groups compared to 32.8% with placebo

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[PMID: 15636457] PubMed record related to this compound for laboratory literature review

Expert consensus on clinical application of glucagon like peptide-1 receptor agonist in the treatment of type 2 diabetes [J]

Circ Res (2001) 89:44552