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Mediat Inflamm 2015:810948 Altuntas A, Yilmaz HR, Altuntas A, Uz E, Demir M, Gokcimen A, Aksu O, Bayram DS, Sezer MT (2014) Caffeic acid phenethyl ester protects against amphotericin B induced nephrotoxicity in rat model

These approaches are not mutually exclusive

4 DPP-4 inhibitors decrease serum DPP-4 enzyme activity responsible for degradation of GLP-1 by more than 80% and thereby restore GLP-1 to physiologic levels

Individuals with a positive screening test result for hepatitis B surface antigen, hepatitis C virus antibody, or HIV types 1 or 2 antibodies were excluded

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From there, the GLP-1 medication enters the bloodstream and begins working in much the same way as an injection