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Although the full mechanism of action is unknown, it can activate nuclear factor erythroid 2related factor 2 (Nrf2), modulate GSH and inflammasome to block correct antigen presentation by dendritic cells thereby signifying the role of GSH in improving psoriasis

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This enzyme converts cysteine to cystathionine and its absence in egtA 26933 may be to ensure cysteine flux is available to facilitate increased GSH biosynthesis (Supplementary Table S1)

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