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Although danuglipron showed good weight loss in phase II trials, the drug was discontinued when a trial participant suffered liver damage

However, it is important to remember that individual results will vary, with some people losing less weight and others losing more

Patients were asked about their experience with GLP-1 usage, and the responses were analyzed to find the biggest trends among users

Feb 23, 2026 What if the real reason your GLP-1 oral liquid is not working has nothing to do with the formula itself, but everything to do with how often you take it

It should also not be taken with certain psychiatric medications that increase serotonin levels

Put another way, muscle accounted for 21.6% of the total weight lost, comparable to the roughly 25% attributed to weight loss from dieting2