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Liver injury, in slides blinded to treatment and grouping, was scored by an experienced histologist (DO) as previously described 24,25 and included assessment of features of hepatocyte injury, the presence of inflammatory cells and foci, steatosis, and markers of tissue response

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Importantly, experimental observations consistently show that AOD 9604 does not activate the growth hormone receptor or alter IGF-1 signaling pathways [4]

Different studies use different concentrations, delivery systems, endpoints, and model organisms

[5] Although it is named for Rancho Santa Margarita y Las Flores, which was in San Diego County, the city limits fall within the borders of Rancho Mission Viejo

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