Its Phase 2 obesity trial published in Lancet Diabetes & Endocrinology (2024) showed up to 18.7% weight loss at 46 weeks, while a separate Phase 2 MASH trial demonstrated significant MASH resolution, earning FDA Breakthrough Therapy Designation
Ozempic can be used alone or in combination with other diabetes medications, such as metformin or sulfonylureas
Robbins, Zachary
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Originally designed to treat type 2 diabetes, these medications are now approved for weight management due to their impressive results in promoting healthy, sustainable weight loss
[link] Lluri Gentian, Renella Pierangelo, Finn J Paul, Vorobiof Gabriel, Aboulhosn Jamil, Deb Arjun, " Prognostic Significance of Left Ventricular Fibrosis in Patients With Congenital Bicuspid Aortic Valve", The American journal of Cardiology (2017)