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Moreover, neonatal cells appear to compensate for the infection-dependent mitochondrial dysfunction by extramitochondrial ATP production, and proliferating cells are particularly susceptible to apoptosis induced by oxidative stress 105
GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor
The redox status has been suggested to regulate stem cell self-renewal and differentiation, and accumulating evidence indicates that stem cells undergo self-renewal in the environment with low ROS levels, while ROS levels increase in differentiated stem cells [117, 118]
Studies show significantly increased collagen, reticulin, and blood vessel formation[9]
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