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Acknowledgements The authors thank the Vice Chancellor of the Mashhad University of Medical Sciences, Mashhad, Iran

While the SURPASS clinical trial programme has provided valuable data on metabolic outcomes, studies specifically examining inflammatory parameters are more limited

Noteworthy, rare infections include tuberculosis (TB), with common infections including candidiasis and respiratory tract infections

Sci Transl Med 5(209):209ra151

245 Sleep loss is known to activate the bodys stress signaling network, which can further aggravate sleep disruption

Warm, humid weather can create conditions that encourage both bacterial and yeast overgrowth on the skin