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The molecular mechanisms by which GLP-1RAs influence cancer risk involve complex intracellular signaling networks

Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)

J Ay PubMed Sharifi Razavi A, Mohajerani F, Niksolat F, Karimi N

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