These symptoms are more likely at the beginning of taking semaglutide and will decrease with time
If you have severe or intolerable side effects such as nausea, vomiting, diarrhea, constipation, worsening of fatigue, and dizziness, your healthcare provider will pause the medication for a few weeks and keep you on the previous tolerable dose
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When drawing up a dose from a refrigerated vial, you can inject cold or let the syringe warm for a minute or two in your hand
The appetite suppression is strong, and metabolic effects are well-established
Their website references a 6-month clinical trial of 180 participants taking semaglutide or tirzepatide alongside the WW Clinic programme (Heinberg et al.)