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Proton pump inhibitors (PPIs) and H2-receptor antagonists reduce gastric acid production, impairing the release of B12 from dietary proteinsthough intrinsic factor-mediated absorption of synthetic B12 remains largely intact
Adults usually need 2.4 mcg a day
No perceived negative side effects
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Each rabbit was observed individually in a controlled ground area for 20 minutes daily at a set time
At the 12 mg dose, nausea was reported by approximately 45% of participants
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