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Individuals experiencing nausea from GLP-1 medications may prefer unflavoured or naturally flavoured options

The study protocol was pre-registered in ClinicalTrials.gov under the registry number NCT03533556 ( 23/05/2018)

This expression was evident in ARC, PVN, periaqueductal gray (PAG), AP (area postrema), LPB, and IML of spinal cords, but not in the hippocampus, cortex, basal ganglia, suggesting that GLP-1RAs may be activating the CNS via multiple neuroendocrine pathways

And building a clinical relationship with a provider who understands the full landscape, who can prescribe currently approved agents while monitoring the retatrutide pipeline, and who will be prepared to transition protocols as commercial availability arrives, may be the most strategically sound choice for most patients right now

10.1021/jf0525277 41 OloyedeO

De Jonge CJ, et al