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Patients with renal impairment taking compounded semaglutide may be at a higher risk of acute kidney injury, and those without known underlying renal disease may also experience kidney-related issues

Additionally, adequate sleep (typically 69 hours nightly for adults, per NHS guidance) and stress management support hormonal balance, including optimal GLP-1 function, as chronic stress and sleep deprivation can impair incretin responses

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The good news is that catching and treating it early significantly improves outcomes

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Secondary endpoints were the change from baseline in body weight, fasting serum glucose, and glucose assessed by continuous glucose monitoring