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Theoretical concerns include off-target cell death, immune burden from clearing many cells at once, impaired wound healing, and injection-site irritation
Evidence ledger: what the data actually show How do they stimulate GH release, with specific numbers
10.1016/j.neuron.2015.03.035 Neuron 97 MaheshwariS.Vilema-EnrquezG.Wade-MartinsR
doi: 10.1038/s41598-021-97130-9 291 AfshariMRahimmalekMMiroliaeiM
Two different selenium-dependent iodothyronine deiodinases (DIOs type 1 and 2) can deiodinate T 4 , thus increasing circulating T 3 , while a third iodothyronine deiodinase (DIO type 3) can convert both T 3 and T 4 to inactive metabolites ( Figure 3 ) (10, 11)
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