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As brand-name supply has partially recovered, some patients have continued using compounded formulations due to lower out-of-pocket costs, faster prescription turnaround, and dose customization options
Lilly is studying retatrutide in several phase 3 clinical trials to evaluate its potential efficacy and safety across several indications, including obesity and overweight with 1 weight-related medical problem, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease
Additionally they do not need SUOX SNPs to have this happen (they may have it, but it isnt necessary)
But it does come with considerations worth thinking through
It was approved by the FDA in 2020 for managing excess weight and is considered one of the few prescription-only anti-obesity medications
As we age, glutathione levels in the body gradually decrease, which can lead to increased oxidative stress and premature aging
