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It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

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These costs should be weighed against the incomplete evidence base

It is generally accepted that mammalian brain function should be studied in mammals, but far too often tissues from rats or mice younger than 4 weeks are studied

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Yan Li, University of California, San Francisco, United States Updates Copyright 2020 Gonen, Moffat, Kwan, OBrien, Desmond and Lui