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Direct Vasodilators Mechanism: Relax arteriolar smooth muscle directly systemic vascular resistance Examples: Hydralazine, Minoxidil Key Points: Usually add-on therapy for resistant hypertension To view or add a comment, sign in BEYOND THE SURFACE: THE THERAPEUTIC REVOLUTION IN PSORIASIS Plaque psoriasis is not just a skin condition but a systemic inflammatory disease that requires a stratified and personalized clinical approach

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10.1016/j.jss.2019.09.011 60 FuS.MengX.FanJ.YangL.WenQ.YeS.et al (2014)

Injectable anti-ageing protocol: 12 mg daily or 5 days on / 2 off , cycle 30 days on / 14 days off , minimum 23 cycles for substantial change Topical anti-ageing protocol: 2 %3 % serum, twice daily, minimum 12 weeks continuous use, paired with daily SPF 50 sunscreen Combination protocol: low-dose injectable ( 1 mg 3/week) + topical 2 % serum daily - typically the most powerful approach for patients 40+ See our related pieces on anti-ageing treatments in Mumbai and how to look younger without looking fake