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Glycated mucosal proteins also impair the binding of defensins (natural antifungal peptides) to mucosal surfaces, reducing local antifungal defence

The change of oxidative stress products in diabetes mellitus and diabetic retinopathy

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During the ischemia phase, ATP depletion triggers dysfunction of cellular ion pumps, leading to intracellular calcium overload and loss of mitochondrial membrane potential, thereby inducing early energy metabolism disorders