Chrisman says the introduction of oral GLP-1s as an inflection point, noting that more new pill approvals as early as 2026 are set to reshape demand
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However, based on the clinical trial criteria used in studies such as the Phase 2 trial published in the New England Journal of Medicine (2023), researchers have investigated its use in adults with: Obesity , defined as a body mass index (BMI) of 30 kg/m or above Overweight (BMI 27 kg/m or above) with at least one weight-related comorbidity, such as hypertension, dyslipidaemia, or obstructive sleep apnoea Type 2 diabetes , where improved glycaemic control alongside weight reduction is a treatment goal In clinical trials, participants were typically adults without a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)
If you wait too long to engage your provider, you may have to go all the way back to your initial starting dose. If your dose is not currently available Sometimes, manufacturer shortages force a treatment gap beyond your control
This is one of the most common questions I hear in my practice
There is no established contraindication, but there is also limited data on interactions