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These features arise from yeasts secreting and extracellularly accumulating glutathionea ubiquitous heat-damage-preventing antioxidant

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Moreover, as pointed by Martins-Filho et al

ODriscoll et al., 2021) which is directly related with the cytokine storm (Fajgenbaum and June, 2020

This upregulation in malignant conditions drives immune evasion through the activation of the STAT3-S100A8/A9 axis, a pathway known for promoting tumor progression and immune suppression

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