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Numerous cell types, including endothelial cells, tanycytes, and neurons in the hypothalamus and hindbrain express GLP- 1, GIP receptors and glucagon receptor, and

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Clinical trials showed patients lost an average of 5% body weight by approximately 12 weeks, with continued weight loss through 72 weeks

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5.3 Ferroptosis-targeted therapeutic strategies in coronary heart disease 5.3.1 Inhibiting ferroptosis in coronary atherosclerotic plaques The pathogenesis of coronary atherosclerotic plaques involves iron accumulation and lipid peroxidationhallmarks of ferroptosis