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The consideration of cysteine during these simulations were important, as cytosolic cysteine is the rate limiting amino acid precursor for synthesis of GSH, via the -glutamylcysteine synthetase (GCS) enzyme, and this is a function of its reduced concentration compared to the other precursors, glycine and glutamate
In September 1986 Mojsov and Habener's team published a joint article which drew very heavily on Mojsovs experiments and analysis
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