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Most absorption problems aren't treatable but a few are - notably h pylori infection - which would mean that once that has been dealt with you would be able to absorb B12 from your diet so wouldn't need maintenance shots for life

Whether this amount produces meaningful physiological effects compared to placebo has not been rigorously tested

At the lab, you might feel a prick or sting as a very thin needle is put into one of your veins

Unopened vials stored at room temperature are typically stable for 2-3 years (check the expiration date)

Much of the evidence comes from mechanistic studies, case reports, and retrospective analyses

B12 shots FAQs What does a B12 shot do for you