SURMOUNT-1 (N=2,539) showed mean weight reductions of 15.0%, 19.5%, and 20.9% at the 5 mg, 10 mg, and 15 mg doses respectively at 72 weeks, compared to 3.1% with placebo
The measurement accuracy problem at small volumes The arithmetic above produces some very small volumes, and small volumes carry disproportionate error: A 3-unit draw is close to the resolution limit of the instrument, compounded by hub dead space and meniscus reading
Atlanta, GA: Centers for Disease Control and Prevention, U.S
De National Institute of Dental and Craniofacial Research makes the same point, advising that a sore, lump, patch, or area of bleeding in the mouth lasting more than two weeks should be seen by a dentist or a doctor, and noting that the soft-tissue examination is painless and takes only a few minutes
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MDPI, 2022)