Intracellular Glu is produced from glutamine (Gln) catalyzed by glutaminase (GLS, with two different isomers GLS1 and GLS2) [29, 30]
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(Galerneau et al., 2020.) GH affects the immune, cardiovascular, and central nervous systems, too
There is a wealth of data identifying DPP-4 as a receptor or ligand for a variety of different molecules which, either alone or in combination with its enzymatic activity, allow it affect physiological processes such as the interaction between cells and the extracellular matrix, cell migration, and proliferation
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[PubMed] Melkonian EA, Asuka E, Schury MP