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Fades Dark Spots, Melasma & Hyperpigmentation

Beyond this, its potency may begin to decline

Platelets contain alpha granules packed with growth factors: platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-B), insulin-like growth factor (IGF-1), and others

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Finally there is a substantial body of cell-culture observation on fibroblast behavior, including proliferation, migration and matrix deposition, with a smaller keratinocyte literature alongside it