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Incretin-based therapies: focus on effects beyond glycemic control alone

Avoid combining it with highly acidic or basic solutions, as this can compromise stability

Do not use in pregnant, lactating women and children under 18 years of age

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While the clinical relevance of these findings in a population largely free from kidney disease remains uncertain, the reductions in albuminuria, blood pressure, and the favourable safety profile support further investigation of retatrutides potential kidney-protective effects in high-risk populations

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