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While this may not be applicable to all patients, for those who have achieved sufficient weight loss, gradually extending the injection interval is a promising strategy to reduce the burden while maintaining the effects, the research team stated

Morfeld M, Petersen C, Krger-Bdeker A, Von Mackensen S, Bullinger M

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This dual action is why research suggests it may support weight loss more effectively for some individuals than medications that only target the GLP-1 receptor

For example, in clinical trials of semaglutide (Ozempic) for type 2 diabetes, headaches were reported in approximately 4-8% of patients depending on dose