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There is, however, a synthetic analog of TH4 called TB-500, which has been investigated as a treatment for neurodegenerative conditions like multiple sclerosis, but its use is still largely experimental [4]
Its palmitic acid modification enhances skin penetration, and its established safety profile in cosmetic concentrations (28%) makes it suitable for consumer product development
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Results may include smoother texture, improved firmness, reduced fine lines, and a brighter, more even tone
Some users optimize at 1%, others at 3% or higher
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