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When combined, the inhibition of NF-B or p38 MAPK may impact ROS/RNS production and reduce the generation of cytokines in patients with IBD, particularly when the disease is actively progressing (167)

Regular follow-up appointments are scheduled throughout treatment to monitor progress, assess results, and make dosage adjustments where needed

These results for valproic acid alone suggest the downstream Wnt activation has independent value, which combines with PTD-DBM upstream effects for enhanced outcomes

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X.RanQ.DuanQ.JinJ.WangY.YuL.et al (2024b)